The Carman Li laboratory in the Department of Cancer Biology at the University of Pennsylvania is hiring a Research Specialist A/B. The Li lab studies unexplored mechanisms and therapeutic opportunities of hereditary cancers, particularly BRCA1/2 breast cancers, with the ultimate goal of improving patient outcomes. We use advanced methodologies, including genetically engineered mouse models, organoid cultures, patient samples, and single-cell omics. This is an excellent opportunity to learn a wide array of in vivo, in vitro, and molecular techniques, contribute to cutting-edge research, and help advance the frontiers of cancer biology. The Li lab values a supportive and collaborative environment. Former trainees mentored by Dr. Li have earned publication authorship and successfully transitioned to graduate/medical schools and industry positions. Successful candidates will have a strong background in biology, be highly motivated, and have excellent organizational skills. Responsibilities include supporting daily lab operations and contributing to research projects. Position is contingent upon continued grant funding. Job Responsibilities include assisting lab operations (ordering, inventory, organization, maintenance of equipment and reagents), contributing to research projects (mouse work, 2D cell and 3D organoid cultures, molecular, cell, and tissue analyses including DNA cloning, CRISPR/RNAi gene perturbation, DNA/RNA/protein analysis, flow cytometry, histology). The RS-B position will also assist with training lab members, including students and postdocs. Other duties as assigned. Qualifications for RS-A: Bachelor of Science and 0 to 1 years of experience or equivalent; for RS-B: Bachelor of Science and 1 to 3 years of experience or equivalent. Experience required in mouse models of cancer, cell/organoid culture, lab management. Candidates must be highly motivated, have good work ethic, work independently and as a team, follow protocols with attention to detail, produce accurate and high-quality work, think creatively to solve problems, and have excellent communication, organization, and time management skills.
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